Plant Breeding and Biotechnology

Table. 2. Table 2

Techniques involved in enhancing COs frequency in major crops.

Crop	Technique	Increased fold COs rate	Reference
Tomato	Solanum lycopersicoides introgression lines and interspecific hybrids with L. pennellii hybrids	3 to 10-fold	Canady et al. 2006
Brassica napus	Haploid × euploid B. napus hybrids	10 to 100-fold	Nicolas et al. 2007
Tomato	MMR inhibitions (RNAi of SlMSH7, AtMSH2-DN)	3.8 to 29.2%	Tam et al. 2011
Brassica napus	AAC hybrid with an extra chromosome 9 (C9)	2.7-fold	Suay et al. 2014
Rice	recq4 single mutant	∼3-fold	Mieulet et al. 2018
Pea	recq4 single mutant	∼3-fold	Mieulet et al. 2018
Tomato	recq4 single mutant	∼3-fold	Mieulet et al. 2018
Hexaploid Wheat	Hpp-5Mg/ph1bph1b genotypes double monosomic for T7BS.7S#3L/7B in wheat-Th. intermedium hybrids	100-fold	Koo et al. 2020
Barley	Hybridization between cultivated barley and wild barley accessions	1.4-fold	Dreissig et al. 2020
Brassica napus	AAC allotriploid hybrids	3.7-fold	Boideau et al. 2021
Hexaploid Wheat	TaMSH7-3D loss-of-function in wheat/rye hybrids	Up to 5.5-fold	Serra et al. 2021
Hexaploid wheat (newly synthetized)	Hybrids of tetraploid Triticum turgidum and diploid Aegilops tauschii followed by WGD	2.3-fold	Wan et al. 2021
Tomato	CRISPR/Cas inactivation of RECQ4	1.53-fold	de Maagd et al. 2020
Tetraploid wheat	Virus-Induced gene Silencing (VIGS) of genes XRCC2 and FANCM	Up to 93% in the pericentromeric regions	Raz et al. 2021
Wheat	TaMSH7-3D mutation in hexaploid wheat × Ae. variabilis hybrid	5.5-fold	Soares et al. 2021
Barley	Induced mutation in HvRECQL4	2-fold	Arrieta et al. 2021